A recent study found that drinking three cups of coffee or consuming 200–300 mg of caffeine daily can help reduce the risk of developing cardiometabolic diseases. Caffeine can help improve cardiometabolic health by lowering inflammation, however, when you consume excess caffeine, it can have negative side effects. The study was published online ahead of print in the Journal of Clinical Endocrinology & Metabolism.

According to The University of Edinburgh, cardiometabolic diseases are a group of common but often preventable conditions including heart attack, stroke, diabetes, insulin resistance and non-alcoholic fatty liver disease. Previous studies have shown the protective effects of coffee, tea and caffeine against these diseases, however, their impact on cardiometabolic multimorbidity has remained largely unknown, says a report in Healthline.

The new study says that moderate consumption of coffee and caffeine can help reduce the risk of developing multiple cardiometabolic diseases in healthy adults when compared to consuming little to none.

For the study, the researchers used data from the UK Biobank. This data included the information of over 500,000 residents of the United Kingdom aged between 40 to 69 about their diet and health.

The researchers focused on participants who had completed at least one dietary questionnaire and excluded those with pre-existing cardiometabolic conditions or incomplete data on coffee or tea consumption. The analysis examined the caffeine consumption of 172,315 participants and the coffee and tea intake of 188,091 participants.

The participants were then categorized based on the estimated average coffee and tea intake (0, 1, 2, 3, 4, 5, or more drinks per day) and estimated total caffeine intake per day in milligrams (mg) from regular coffee and tea, ranging from 0 to 100 mg daily to over 400 mg daily.

The Healthline report also says that the study also analyzed 168 metabolites to identify those associated with coffee, tea, and caffeine consumption and new cases of cardiometabolic multimorbidity among large subsets of participants.

After following up with the participants for an average of 11.7 years, the researchers found that less than 1% of participants developed cardiometabolic multimorbidity. Based on their initial caffeine intake, 135,844 participants (78.83%) consumed over 100 mg daily, with most (96.10%) consuming less than 400 mg daily.

The study found that consuming moderate levels of coffee and caffeine can help lower the risk of developing multiple cardiometabolic diseases.

Drinking three 8-ounce cups of coffee or consuming 200–300 mg of caffeine daily was linked with 48.1% or 40.7% lower risk of cardiometabolic multimorbidity when compared to nonconsumers or those with less than 100 mg of daily caffeine intake.

The researchers concluded that consuming moderate amounts of coffee or caffeine can help prevent healthy adults from developing cardiometabolic multimorbidity.

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